Thermo Fisher Scientific Fatty Acid Binding Protein (Liver)/FABP1 Monoclonal Antibody (FABP1/3940)
인간 FABP1(L-FABP)을 인식하는 Mouse monoclonal antibody. Western blot, IHC, Peptide Array 등에 사용 가능. 단백질 대사 및 지방산 결합 단백질 연구에 적합. Protein A/G 정제, 4°C 보관, 200 µg/mL 농도.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
| Immunoelectrophoresis (IE) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FABP1/3940 |
| Immunogen | Human recombinant FABP1 protein fragment (around aa1–127) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is stable for 24 months.
- Positive Control: Liver or colon carcinoma tissues (IHC); Human kidney tissue lysate (WB)
- Cellular Localization: Cytoplasm, Nucleus
Specificity Comments:
Fatty acid-binding proteins (FABPs) are a family of homologous cytoplasmic proteins expressed in a tissue-specific manner, playing key roles in lipid and carbohydrate metabolism. FABPs mediate fatty acid and hydrophobic ligand uptake, transport, and targeting. They are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP), striated muscle and heart (H-FABP), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP), and testis (T-FABP).
FABP1 (L-FABP) expression is influenced by developmental, hormonal, dietary, and pharmacological factors, and is essential for cholesterol synthesis and metabolism.
Target Information
FABP1 encodes the fatty acid binding protein found in the liver. These small, conserved cytoplasmic proteins bind long-chain fatty acids and hydrophobic ligands. FABP1 and FABP6 can also bind bile acids. FABPs are involved in fatty acid uptake, transport, and metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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