Thermo Fisher Scientific C1r Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human C1r. Recombinant protein control fragment (Product #RP-105682). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C1r,uniProtId:P00736-1,ncbiNodeId:9606,antigenRange:275-468,antigenLength:705,antigenImageFileName:PA5-64877_C1r_P00736-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64877_C1r_P00736-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662336

Product Specific Information

Immunogen sequence: DLDTSSNAVD LLFFTDESGD SRGWKLRYTT EIIKCPQPKT LDEFTIIQNL QPQYQFRDYF IATCKQGYQL IEGNQVLHSF TAVCQDDGTW HRAMPRCKIK DCGQPRNLPN GDFRYTTTMG VNTYKARIQY YCHEPYYKMQ TRAGSRESEQ GVYTCTAQGI WKNEQKGEKI PRCLPVCGKP VNPVEQRQRI IGGQ

Highest antigen sequence identity to the following orthologs - mouse 84%, rat 87%.

Target Information

C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s. C1r has a molecular weight of 83,000 and is present in plasma in an average concentration of 50 µg/mL, either as a complex with C1q and C1s or in the absence of C1q as a tetramer with C1s. The subcomponents of the C1 complex are responsible for the initiation of the classical pathway of complement activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.