
Thermo Fisher Scientific ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Monoclonal Antibody (57)
ACTH 단일클론 항체로 뇌하수체 마커 연구에 적합. 인간, 마우스, 랫트 반응성. IHC, ICC, Flow, ELISA 등 다양한 응용 가능. Protein A/G로 정제된 액상 형태로 4°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 57 |
| Immunogen | Recombinant fragment corresponding to human ACTH (N-terminal) conjugated to keyhole limpet haemocyanin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ACTH (adrenocorticotropic hormone) plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also produces MSH and beta endorphin. ACTH is secreted from the anterior pituitary in response to corticotropin-releasing hormone from the hypothalamus. It stimulates glucocorticoid secretion (e.g., cortisol) but has limited influence on mineralocorticoid (aldosterone) secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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