Thermo Fisher Scientific HMGB2 Polyclonal Antibody
HMGB2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, ICC/IF, ELISA에 사용 가능하며 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 저장되며 -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100–200 of human HMGB2 (NP_002120.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.44 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914118 |
Product Specific Information
Positive test controls include: HeLa, 293T, U-87MG, RAW264.7, PC-12.
The target is usually found in the following locations: Chromosome, Cytoplasm, Nucleus, Secreted.
Immunogen sequence:
SAFFLFCSEH RPKIKSEHPG LSIGDTAKKL GEMWSEQSAK DKQPYEQKAA KLKEKYEKDI AAYRAKGKSE AGKKGPGRPT GSKKKNEPED EEEEEEEEDE D
Target Information
HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. Proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies show that HMGB2 can efficiently bend DNA and form DNA circles, suggesting a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. It is also implicated in the final ligation step in DNA end-joining repair and V(D)J recombination.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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