Thermo Fisher Scientific RIG-I Recombinant Rabbit Monoclonal Antibody (7F6)
Thermo Fisher Scientific의 RIG-I 재조합 토끼 단클론 항체(7F6)는 인간 RIG-I 단백질을 인식하며 IHC(P) 및 ELISA에 사용됩니다. HEK293 세포에서 발현된 고순도 항체로, 액상 형태이며 PBS/glycerol 버퍼에 보관됩니다. 바이러스 dsRNA 인식 연구에 적합합니다.
- 카탈로그번호
- MA549920
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RIG-I Recombinant Rabbit Monoclonal Antibody (7F6)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7F6 |
| Immunogen | A synthesized peptide derived from human DDX58 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092806 |
Target Information
Retinoic acid-inducible gene I (RIG-I) is a pattern recognition receptor (PRR) that detects viral double-stranded RNA (dsRNA) and activates the innate immune response. Together with MDA5, RIG-I mediates recognition of viral RNA and triggers signaling through IPS-1, leading to activation of NF-kappaB and IRF-3, apoptosis, cytokine signaling, and inflammation.
RIG-I is critical for immune signaling against viruses such as influenza A and B, human respiratory syncytial virus, paramyxoviruses, Japanese encephalitis virus, and West Nile virus. MicroRNA-146a negatively regulates RIG-I-dependent antiviral responses by targeting TRAF6, IRAK1, and IRAK2. Additionally, RIG-I has been implicated in the detection of cytosolic DNA through RNA polymerase III activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.