Thermo Fisher Scientific Phospho-KV4.2 (Ser616) Polyclonal Antibody
Phospho-KV4.2 (Ser616) 항체로, 인간 Kv4.2/KCND2의 Ser616 인산화 부위를 인식합니다. Rabbit Polyclonal IgG 형식이며 IHC(P)에서 1:50~1:100 희석으로 사용됩니다. 액상 형태, 1 mg/mL 농도, -20°C 보관 조건입니다.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Kv4.2/KCND2 around the phosphorylation site of Ser616 (P-E-SP-P-E) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555254 |
Target Information
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes—shaker, shaw, shab, and shal—have been identified in Drosophila, and each has been shown to have human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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