Thermo Fisher Scientific SFRS15 Polyclonal Antibody
Thermo Fisher Scientific의 SFRS15 폴리클로날 항체는 인간 SFRS15 단백질에 특이적으로 반응하는 Rabbit IgG 항체입니다. IHC와 ICC/IF 실험에 최적화되어 있으며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA553838
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SFRS15 (Recombinant protein control fragment: Product #RP-91821) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647189 |
Product Specific Information
Immunogen sequence:
PITPPVSIPP PHTPPISIPN STIAGINEDT TKDLSIGNPI PTVVSGARGN AESGDSVKMY GSAVPPAAPT NLPTPPVTQP VSLLGTQGVA PGPVIGLQAP STGLLGARPG LIPLQRPPGM P
Highest antigen sequence identity to orthologs:
- Mouse: 98%
- Rat: 78%
Target Information
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are essential for constitutive splicing and regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites.
Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domain. SFRS15 interacts with the C-terminal repetitive domain (CTD) of Pol II and is believed to link transcription and pre-mRNA processing both functionally and physically.
Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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