Thermo Fisher Scientific CD41 Monoclonal Antibody (VIPL3), FITC
인간 CD41 항원을 인식하는 VIPL3 클론의 마우스 단일클론 항체로, FITC 형광 표지되어 있습니다. Flow Cytometry에 적합하며 높은 형광 효율과 수용성이 우수합니다. 혈소판 관련 연구 및 혈액응고 메커니즘 분석에 활용됩니다.
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Applications
- Flow Cytometry (Flow)
- Tested Dilution: Assay-Dependent
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VIPL3 |
| Immunogen | Human CD41 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 4 mg/mL BSA |
| Contains | 0.1% Sodium Azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10392553 |
Additional Formats
Product Specific Information
FITC conjugates provide high absorptivity, excellent fluorescence quantum yield, and good water solubility, making them suitable for flow cytometry and fluorescence-based assays.
Target Information
CD41 (platelet glycoprotein IIb, ITGA2B) consists of two subunits (α: 120 kDa, β: 23 kDa) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor.
It plays a key role in blood coagulation by mediating platelet aggregation. Upon vascular injury, CD41 binds to proteins such as von Willebrand factor, fibrinogen, fibronectin, and vitronectin.
CD41 is mainly expressed in the megakaryocyte-platelet lineage and is involved in early hematopoietic differentiation.
Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia and Platelet type-16 bleeding disorder.
Classification
Analyte Specific Reagent
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