Thermo Fisher Scientific CaMKII Pan Recombinant Rabbit Monoclonal Antibody (23GB5920)
CaMKII 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 유세포분석에 적합. 인간 및 생쥐 시료에 반응하며, 액상 형태로 공급. Affinity chromatography로 정제되었으며, -20°C에서 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5920 |
| Immunogen | A synthesized peptide derived from human CaMKII (1–88 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) constitute a structurally related subfamily of serine/threonine kinases, including CaMKI, CaMKII, and CaMKIV.
CaMKII is a ubiquitously expressed serine/threonine protein kinase activated by Ca²⁺/calmodulin binding and autophosphorylation. It regulates the cell cycle, transcription, dendritic spine and synapse formation, neuronal plasticity, and sarcoplasmic reticulum Ca²⁺ transport in skeletal muscle.
In neurons, CaMKII plays a structural role in actin cytoskeleton reorganization during plasticity by binding and bundling actin filaments in a kinase-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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