Thermo Fisher Scientific TBX18 Polyclonal Antibody

Thermo Fisher Scientific TBX18 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000 dilution

Product Specifications

Target Information

The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The Tbx gene family is largely conserved throughout metazoan evolution and codes for putative transcription factors that share a uniquely defining DNA-binding domain. Tbx genes are developmental regulators with more than 20 members identified in invertebrates and vertebrates. Mutations in Tbx genes are associated with several human diseases. Functional mechanisms of Tbx products have been mainly studied in T/Brachyury, a transcription activator. The Tbx genes constitute a family of transcriptional regulatory genes implicated in various developmental processes, including germ layer formation and central nervous system patterning.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.