Thermo Fisher Scientific MCM7 Polyclonal Antibody
MCM7 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫트에 반응하며, 고순도 Affinity Chromatography 정제 및 PBS/glycerol 저장 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MCM7 (Accession P33993), corresponding to amino acid residues D382–G432 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900190 |
Product Specific Information
Antibody detects endogenous levels of total MCM7.
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication. The hexameric MCM complex is a key component of the pre-replication complex (pre_RC) and may be involved in replication fork formation and recruitment of other DNA replication-related proteins. The complex consisting of MCM7 along with MCM2, 4, and 6 possesses DNA helicase activity and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase (CDK4) associates with MCM7 and may regulate its interaction with the tumor suppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-115554_MCM7_P33993-1_Rabbit.svg, PA5-115554_MCM7_P33993-1_Rabbit_PDP.jpeg)
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