Thermo Fisher Scientific Human LEMD2 Synthetic Peptide
휴먼 LEMD2 중심부 16개 아미노산 서열 기반의 합성 펩타이드로, PA5-34397 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태이며 PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 포함. 인간 반응성, 연구용 전용 시약.
- 카탈로그번호
- PEP1439
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 16 amino acid sequence near the center of human LEMD2.
PEP-1439 can be used as a blocking peptide with polyclonal antibody PA5-34397.
Target Information
The LEM (lamina-associated polypeptide-emerin-MAN1) domain is a motif shared by a group of lamin-interacting proteins of the inner nuclear membrane (INM) and nucleoplasm.
LEMD2 (LEM domain-containing protein 2) is a lamina-associated protein in the INM involved in nuclear structure organization, containing an N-terminal LEM motif, two transmembrane domains, and a MAN1-Src1p C-terminal (MSC) domain.
LEMD2 is a truncated paralog of MAN1, lacking the MAN1-specific C-terminal RNA-recognition motif, but like MAN1 is required for myogenic differentiation.
Mutations in LEMD2 are thought to be among the possible causes of muscle disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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