Thermo Fisher Scientific CTLA4 Monoclonal Antibody (1F4)
CTLA4 단백질을 인식하는 Mouse IgG2a 단클론 항체로, 인간 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 액상 형태로 제공됩니다. 연구용으로만 사용되며, -20°C 보관 및 동결·해동 반복을 피해야 합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F4 |
| Immunogen | CTLA4 (NP_005205, 36 a.a. approximately 135 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KAMHVAQPAV VLASSRGIAS FVCEYASPGK ATEVRVTVLR QADSQVTEVC AATYMMGNEL TFLDDSICTG TSSGNQVNLT IQGLRAMDTG LYICKVELMY
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances cell activation, CTLA4 inhibits T-cell function. Intracellular CTLA4 is also found in regulatory T cells and may play a key role in their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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