Thermo Fisher Scientific RASSF1 Monoclonal Antibody (OTI9A5), TrueMAB
인간 RASSF1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot 및 Immunocytochemistry에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 저장용 PBS/BSA/glycerol 버퍼 포함. 암 관련 연구용으로 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9A5 |
| Immunogen | Full length human recombinant RASSF1 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, suggesting its tumor suppressor function. Inactivation of this gene correlates with hypermethylation of its CpG-island promoter region. The encoded protein interacts with DNA repair protein XPA and inhibits cyclin D1 accumulation, inducing cell cycle arrest. Seven alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: TA502511_RASSF1_Q9NS23-1_House_mouse.svg)
(이미지 파일명: TA502511_RASSF1_Q9NS23-1_House_mouse_PDP.jpeg)
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