ELK Biotechnology Rhotekin rabbit pAb
Rhotekin 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 사용 가능. Rho 단백질 신호전달 연구에 적합하며, 인간, 마우스, 랫트에 반응. -20°C에서 1년 보관 가능.
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Rhotekin rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Rhotekin rabbit pAb |
| Alternative Names | RTKN; RTKN1; Rhotekin |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from Rhotekin (AA range: 80-160) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 6242 |
| Human Swiss-Prot No. | Q9BST9 |
| Cellular localization | Cytosol |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth, and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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