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ELK Biotechnology p70 S6 kinase α (phospho Thr412) rabbit pAb
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p70 S6 kinase α의 Thr412 인산화 형태를 인식하는 rabbit polyclonal antibody. WB, IHC, IF, ELISA에 사용 가능. 세포 성장 및 단백질 합성 연구용으로 적합. Human, Mouse, Rat 반응성. -20°C에서 1년 보관.
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- pk
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ELK Biotechnology ES7091-100UL p70 S6 kinase α (phospho Thr412) rabbit pAb, 100UL pk판매 단위 pk ·
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ELK Biotechnology ES7091-50UL p70 S6 kinase α (phospho Thr412) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology p70 S6 kinase α (phospho Thr412) rabbit pAb
제품명
p70 S6 kinase α (phospho Thr412) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase |
| Applications | WB, IHC, IF, ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Thr389 (AA range: 355–404) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kDa |
| Gene ID (Human) | 6198 |
| Human Swiss-Prot No. | P23443 |
| Cellular Localization | Cell junction, synapse, synaptosome, mitochondrion outer membrane, mitochondrion. Colocalizes with URI1 at mitochondrion. Isoform Alpha I: Nucleus, Cytoplasm. Isoform Alpha II: Cytoplasm. |
| Species Reactivity | Human, Mouse, Rat |
Background
Ribosomal protein S6 kinase B1 (RPS6KB1) is a member of the ribosomal S6 kinase family of serine/threonine kinases. This protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Its activity has been associated with various human cancers. Alternatively spliced transcript variants and different translation start sites result in isoforms with distinct subcellular localizations. Two pseudogenes for this gene exist on chromosome 17. (RefSeq, Jan 2013)
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