ELK Biotechnology KCNT1 rabbit pAb
KCNT1 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA 등 다양한 응용 가능. 인간, 생쥐, 랫트 반응성 확인. 세포막 단백질 검출에 적합하며, -20°C에서 1년 보관 가능.
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KCNT1 rabbit pAb
공급업체: ELK Biotechnology
제품 개요
KCNT1 단백질을 인식하는 토끼 유래 다클론 항체로, 다양한 생물종에서 사용 가능하며 여러 분석 응용 분야에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | KCNT1 rabbit pAb |
| Alternative Names | KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/10000 Other applications: Not yet tested |
| Immunogen | Synthesized peptide derived from human KCNT1 (AA range: 1019–1068) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 140 kD |
| GeneID (Human) | 57582 |
| Human Swiss-Prot No | Q5JUK3 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
Potassium channels are among the most complex voltage-gated ion channels in terms of function and structure. They regulate neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
The KCNT1 gene encodes a sodium-activated potassium channel subunit involved in ion conductance and developmental signaling pathways. Mutations in KCNT1 are associated with early-onset epileptic disorders such as malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing produces multiple transcript variants. (RefSeq, Dec 2012)
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