ELK Biotechnology β-1,4-GalNAc-T rabbit pAb

제품명

β-1,4-GalNAc-T rabbit pAb

대체 명칭

CSGALNACT1; CHGN; GALNACT1; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; CsGalNAcT-1; Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT-1

적용 분야 (Applications)

• WB (Western Blot)
• IHC (Immunohistochemistry)
• IF (Immunofluorescence)
• ELISA

권장 희석 배수 (Recommended Dilutions)

면역원 (Immunogen)

• Synthesized peptide derived from human CSGALNACT1 (AA range: 201–250)

제품 정보

유전자 및 단백질 정보

Background

• Catalytic activity: UDP-N-acetyl-D-galactosamine + β-D-glucuronyl-(1→3)-D-galactosyl-proteoglycan → UDP + N-acetyl-D-galactosaminyl-(1→4)-β-D-glucuronyl-(1→3)-β-D-galactosylproteoglycan
• Function: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Plays an important role in chondroitin chain biosynthesis in cartilage.
• Online information: Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; GlycoGene database
• PTM: N-glycosylated
• Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family
• Tissue specificity: Ubiquitous expression, highest in placenta, thyroid, bladder, prostate, and adrenal gland; lower levels in other tissues

Species Reactivity

Human; Mouse; Rat