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ELK Biotechnology Mena rabbit pAb
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Mena 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 ENAH 유래 펩타이드로 면역화되었으며 세포골격 및 세포돌기에서 발현을 탐지할 수 있습니다. 세포 이동성과 부착 관련 연구에 유용합니다.
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ELK Biotechnology ES6754-100UL Mena rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES6754-50UL Mena rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Mena rabbit pAb
제품명
Mena rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ENAH; MENA; Protein enabled homolog |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ENAH (AA range: 472-521) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 67 kD |
| Gene ID (Human) | 55740 |
| Human Swiss-Prot No | Q8N8S7 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cytoplasm; cytoskeleton; cell projection (lamellipodium, filopodium); cell junction (synapse, focal adhesion). Targeted to the leading edge of lamellipodia and filopodia by MRL family members. Colocalizes at filopodial tips with vinculin and zyxlin; with N-WASP at the leading edge; and with GPHN and PFN at synapses (By similarity). |
Background
This gene encodes a member of the enabled/vasodilator-stimulated phosphoprotein family. Members of this family are involved in actin-based motility. This protein regulates actin filament assembly and modulates cell adhesion and motility. Alternate splice variants have been correlated with tumor invasiveness in certain tissues and may serve as prognostic markers. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2016]
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