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ELK Biotechnology PI 3-kinase p85/p55 (phospho Tyr467/199) rabbit pAb
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PI 3-kinase p85/p55 인산화형(Tyr467/199)을 인식하는 토끼 폴리클로날 항체. WB, IHC, IF, ELISA에 사용 가능. 세포 내 PI3K 신호전달 연구에 적합하며, 인간, 생쥐, 랫드, 원숭이, 돼지 반응성 확인됨.
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- ES6591-xxxxx (2개 옵션)
- 판매단위
- pk
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ELK Biotechnology ES6591-100UL PI 3-kinase p85/p55 (phospho Tyr467/199) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES6591-50UL PI 3-kinase p85/p55 (phospho Tyr467/199) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology PI 3-kinase p85/p55 (phospho Tyr467/199) rabbit pAb
제품명
PI 3-kinase p85/p55 (phospho Tyr467/199) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human PI3-kinase p85-alpha/gamma around the phosphorylation site of Tyr467/199 (AA range: 436–485) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 + 85 kDa |
| GeneID (Human) | 5295 |
| Human Swiss-Prot No | P27986 / Q92569 |
| Cellular Localization | Nucleus, cytoplasm, cis-Golgi network, cytosol, plasma membrane, cell-cell junction, phosphatidylinositol 3-kinase complex (class IA), membrane, perinuclear endoplasmic reticulum membrane |
| Species Reactivity | Human; Mouse; Rat; Monkey; Pig |
Background
Phosphatidylinositol 3-kinase (PI3K) phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme consists of a 110 kDa catalytic subunit and regulatory subunits of 85, 55, or 50 kDa. This gene encodes the 85 kDa regulatory subunit, which plays an important role in insulin-mediated metabolic actions. Mutations in this gene have been associated with insulin resistance. Alternative splicing results in four transcript variants encoding different isoforms. (RefSeq, Jun 2011)
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