ELK Biotechnology Peroxin 7 rabbit pAb
Peroxin 7 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA 등에 사용 가능. 인간, 마우스, 랫트 반응성. 세포 내 퍼옥시좀 및 세포질에 위치한 PEX7 단백질 검출에 적합. -20°C에서 1년 보관 가능.
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제품명
Peroxin 7 rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PEX7; PTS2R; Peroxisomal targeting signal 2 receptor; PTS2 receptor; Peroxin-7 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human PEX7 (AA range: 204–253) |
| Host | Rabbit |
| Storage | −20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| GeneID (Human) | 5191 |
| Human Swiss-Prot No | O00628 |
| Cellular Localization | Peroxisome, Cytoplasm |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes the cytosolic receptor for peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with varying phenotypes. Cells from all PBD patients exhibit defects in importing one or more classes of peroxisomal matrix proteins. Defects in this gene are associated with PBD complementation group 11 (PBD-CG11), rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD). [provided by RefSeq, Oct 2008]
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