Thermo Fisher Scientific FAT1 (FAT atypical cadherin 1) Monoclonal Antibody (FAT1-3D7/1)
FAT1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot, ICC/IF, ELISA에 적합합니다. Drosophila Fat 단백질의 세포질 도메인을 면역원으로 제작되었으며, Protein L로 정제된 액상 형태입니다. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FAT1-3D7/1 |
| Immunogen | Cytoplasmic domain of Drosophila Fat protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein L |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product belongs to the cadherin superfamily, characterized by cadherin-type repeats. It contains 34 tandem cadherin-type repeats, five EGF-like repeats, and one laminin A-G domain. The gene is highly expressed in several fetal epithelia and likely functions as an adhesion molecule and/or signaling receptor, playing a critical role in developmental processes and cell communication. Transcript variants from alternative splicing or promoter usage exist but are not fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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