Thermo Fisher Scientific SHQ1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SHQ1. Recombinant protein control fragment (Product #RP-100146). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SHQ1,uniProtId:Q6PI26-1,ncbiNodeId:9606,antigenRange:479-577,antigenLength:577,antigenImageFileName:PA5-60124_SHQ1_Q6PI26-1_Rabbit.svg,antigenImageFileNamePDP:PA5-60124_SHQ1_Q6PI26-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647286

Product Specific Information

Immunogen sequence: ELKDSPSETV SSLQGPFLEE SSAFLIVDGG VRRNTAIQES DASQGKPLAS SWPLGVSGPL IEELGEQLKT TVQVSEPKGT TAVNRSNIQE RDGCQTPNN

Highest antigen sequence identity to the following orthologs: Mouse - 36%, Rat - 32%.

Target Information

SHQ1 is the human homolog of yeast Shq1p, a protein that acts as an accessory factor in the assembly of H/ACA ribonucleoproteins. SHQ1 has been shown to bind the major H/ACA core protein and the pseudouridine synthase NAP57, but precedes the assembly role of NAF1 and of the other H/ACA core proteins. SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.