Thermo Fisher Scientific MTA2 Polyclonal Antibody
MTA2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫드 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MTA2. Recombinant protein control fragment (Product #RP-89363). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789400 |
Product Specific Information
Immunogen sequence:
ECSIRLPKAA KTPLKIHPLV RLPLATIVKD LVAQAPLKPK TPRGTKTPIN RNQLSQNRGL GGIMVKRAYE TMAGAGVPFS ANGRPLASGI RSSSQPAAKR QKLNPADAPN PVVFVATKDT RALRKALTHL EMRRAARRPN LPLKVKPT
Target Information
This gene encodes a protein that is part of the NuRD (nucleosome remodeling deacetylase) complex located in the nucleus of human cells. It is broadly expressed and strongly present in many tissues. The gene family may encode related proteins involved in transcriptional regulation, either directly or indirectly through chromatin remodeling.
It is closely related to another family member associated with metastatic potential in certain carcinomas. Both proteins share similar domains, including DNA binding, dimerization, and methylation-related domains.
One known target of this gene product is p53, whose deacetylation correlates with loss of growth inhibition in transformed cells, suggesting a link between these proteins and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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