Thermo Fisher Scientific HIV1 gp120 Monoclonal Antibody (4F4E4)
HIV-1 gp120 단백질에 특이적인 단클론 항체로, Western blot 및 ELISA에 적합합니다. Mouse IgG2b 아이소타입이며, 비표지 상태로 제공됩니다. 단백질 A로 정제된 액상 형태이며, 방부제가 포함되어 있지 않습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F4E4 |
| Immunogen | Recombinant HIV-1 gp120 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785764 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for HIV-1 gp120.
Target Information
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes.
The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane gp41 subunit to mediate fusion between viral and target cell membranes.
Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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