Thermo Fisher Scientific PPM1E Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 213-459 of human PPM1M (NP_6532423) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PPM1E,uniProtId:Q8WY54-2,ncbiNodeId:9606,antigenRange:213-459,antigenLength:755,antigenImageFileName:PA5-89834_PPM1E_Q8WY54-2_Rabbit.svg,antigenImageFileNamePDP:PA5-89834_PPM1E_Q8WY54-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.75 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805797

Product Specific Information

Immunogen sequence: MGGCTALVAV SLQGKLYMAN AGDSRAILVR RDEIRPLSFE FTPETERQRI QQLAFVYPEL LAGEFTRLEF PRRLKGDDLG QKVLFRDHHM SGWSYKRVEK SDLKYPLIHG QGRQARLLGT LAVSRGLGDH QLRVLDTNIQ LKPFLLSVPQ VTVLDVDQLE LQEDDVVVMA TDGLWDVLSN EQVAWLVRSF LPGNQEDPHR FSKLAQMLIH STQGKEDSLT EEGQVSYDDV SVFVIPLHSQ GQESSDH; Positive Samples: Mouse testis; Cellular Location: Nucleus

Target Information

Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.