Invitrogen™

IgM Mouse ELISA Standard

This product is a component of a respective eBioscience Kit. Please refer to the relevant manual for each product on자세히 알아보기

This product is a component of a respective eBioscience Kit. Please refer to the relevant manual for each product on our website.

Immunoglobulin M is the third most common serum Ig and can exist as both a pentamer and as a monomer (e.g. found on B lymphocytes as B - cell receptors).

The large pentameric structure allows for building of bridges between encountered epitopes on molecules that are too distant as to be connected by smaller IgG antibodies.

IgM is built as the first antibody during an immune response and is responsible for agglutination and cytolytic reactions since its pentameric structure gives it 10 free antigen binding sites in theory and it posseses a high avidity. Due to conformational constraints among the 10 Fab portions, IgM only has a valence of 5. Additionally, IgM is not as versatile as IgG, but it is of vital importance in complement activation and agglutination.

IgM is predominantly found in the lymph fluid and the blood and is a very effective neutralizing agent in the early stages of disease. Elevated levels can be a sign of recent infection or exposure to antigen.

Reported Application
ELISA, ELISA Recombinant Standard

사양

형식Kit

수량4 pack

재조합Recombinant

용도(장비)Microplate Reader

이전 식별자eBioscience

이뮤노어세이 키트 형식ELISA Standard

타겟 종 프라이머리Mouse

타겟 키트 이름 지정IgM

타겟 종 이름지정Mouse

타겟 종 검증Mouse

형태Liquid

Unit SizeEach