Thermo Fisher Scientific SF1 Monoclonal Antibody (OTI7H9), TrueMAB
Human SF1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(Paraffin) 검증 완료. TrueMAB 포맷으로 높은 특이성과 재현성 제공. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–276 of human SF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Splicing factor 1 (SF1) is a nuclear pre-mRNA splicing factor that specifically recognizes the intron branch point sequence at the 3′ splice site, together with the large subunit of U2 auxiliary factor (U2AF). It is required for the early stages of spliceosome assembly and plays a role in nuclear pre-mRNA retention and transcriptional repression.
The protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region that bind a key branch-site adenosine, a zinc knuckles domain, and a C-terminal proline-rich domain.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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