Thermo Fisher Scientific HMGA1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.5–1 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 3.75 µg/mL

Product Specifications

Product Specific Information

• Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
• Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Target Information

HMGA1 encodes a non-histone protein involved in various cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and metastatic progression of cancer cells.
The protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to DNA or proteins.
HMGA1 is frequently acetylated and localized in the nucleus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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