Thermo Fisher Scientific AMZ2 Polyclonal Antibody
Thermo Fisher Scientific의 AMZ2 Polyclonal Antibody는 인간 AMZ2 단백질을 인식하는 토끼 다클론 항체로, WB, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AMZ2. Recombinant protein control fragment (Product #RP-93542) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637924 |
Product Specific Information
Immunogen sequence:
AGEQRLMNEA FQPASDLFGP ITLHSPSDWI TSHPEAPQDF EQFFSDPYRK TPSPNKRSIY IQSIGSLGNT RIIS
Highest antigen sequence identity to orthologs:
- Mouse: 82%
- Rat: 80%
Target Information
AMZ2 (archaelysin family metallopeptidase 2)
Also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, AMZ2 is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene mapped to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis, and also found in kidney, liver, pancreas, lung, brain, and placenta, as well as in fetal tissues such as kidney, liver, lung, and brain.
AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. It is inhibited by general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze Neurogranin or Angiotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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