Thermo Fisher Scientific RASD2 Monoclonal Antibody (OTI1F7), TrueMAB
RASD2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F7 |
| Immunogen | Full length human recombinant protein of human RASD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein predominantly expressed in the striatal region of the brain. It belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and plays a role in normal brain development and function. Mice lacking this gene exhibit increased anxiety and motor coordination deficits. Rhes was identified as TEM2 through gene expression analysis upregulated in tumor endothelium. Tumor endothelial markers are significantly upregulated during angiogenesis and neoangiogenesis, crucial for solid tumor growth. TEMs localized on the cell surface and conserved across species are of interest for anti-angiogenic therapy development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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