Thermo Fisher Scientific Drebrin Polyclonal Antibody
Drebrin 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 적합. 인간 시료 반응성. Antigen affinity chromatography로 정제되었으며 1 mg/mL 농도의 액상 형태. 알츠하이머병 연구 등 신경세포 성장 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Immunoprecipitation (IP)
- Tested Dilution: 20–40 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 484 and 497 of human DBN1 (D0S117E) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in neuronal growth. It belongs to the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer’s disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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