Thermo Fisher Scientific OBFC1 Monoclonal Antibody (OTI2E4)
OBFC1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, ICC/IF, Flow Cytometry에 사용 가능. 인간 시료 반응성, Mouse IgG1 아이소타입. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E4 |
| Immunogen | Full length human recombinant protein of OBFC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724899 |
Target Information
OBFC1 is a component of the CST complex, which binds to single-stranded DNA and protects telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex likely plays a broader role in DNA metabolism at non-telomeric sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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