Thermo Fisher Scientific SMU1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SMU1. Recombinant protein control fragment (Product #RP-92934). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SMU1,uniProtId:Q2TAY7-1,ncbiNodeId:9606,antigenRange:2-106,antigenLength:513,antigenImageFileName:PA5-54062_SMU1_Q2TAY7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54062_SMU1_Q2TAY7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647665

Product Specific Information

Immunogen sequence: SIEIESSDVI RLIMQYLKEN SLHRALATLQ EETTVSLNTV DSIESFVADI NSGHWDTVLQ AIQSLKLPDK TLIDLYEQVV LELIELRELG AARSLLRQTD PMIML

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.