Thermo Fisher Scientific Myotrophin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Myotrophin. Recombinant protein control fragment (Product #RP-92642). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Myotrophin,uniProtId:P58546-1,ncbiNodeId:9606,antigenRange:12-118,antigenLength:118,antigenImageFileName:PA5-54070_Myotrophin_P58546-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54070_Myotrophin_P58546-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644393

Product Specific Information

Immunogen sequence: NGDLDEVKDY VAKGEDVNRT LEGGRKPLHY AADCGQLEIL EFLLLKGADI NAPDKHHITP LLSAVYEGHV SCVKLLLSKG ADKTVKGPDG LTAFEATDNQ AIKALLQ

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3` end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6. 4 kDa tumor antigen that is associated with myeloproliferative disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.