Thermo Fisher Scientific Phospho-Kir1.1 (Ser25, Ser44) Polyclonal Antibody
Phospho-Kir1.1 (Ser25, Ser44) 폴리클로날 항체로, IHC, ICC/IF, peptide-ELISA에 적합합니다. Rabbit IgG 기반이며, 인간 ROMK/Kir1.1 인산화 펩타이드로부터 유래했습니다. 액상 형태로 -20°C 보관하며 연구용으로 사용됩니다.
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Thermo Fisher Scientific Phospho-Kir1.1 (Ser25, Ser44) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| peptide-ELISA (pep-ELISA) | 1:5,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human ROMK/Kir1.1 around the phosphorylation site of Ser44/25 (L-V-SP-K-D) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555302 |
Target Information
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and likely plays an important role in potassium homeostasis. The encoded protein favors potassium influx over efflux. Mutations in this gene have been associated with antenatal Bartter syndrome, characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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