Thermo Fisher Scientific UCP4 Polyclonal Antibody
Thermo Fisher Scientific의 UCP4 Polyclonal Antibody는 Rabbit IgG 기반의 비결합형 항체로 Western blot, ICC/IF, ELISA에 적합합니다. 인간 UCP4 단백질(aa 1–245)을 면역원으로 사용하며, 뇌조직 관련 연구에 유용합니다. -20°C에서 보관하며 동결/해동 반복을 피해야 합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–245 of human SLC25A27 (NP_001190981.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855795 |
Product Specific Information
Immunogen sequence:
MSVPEEEERL LPLTQRWPRA SKFLLSGCAA TVAELATFPL DLTKTRLQMQ GEAALARLGD GARESAPYRG MVRTALGIIE EEGFLKLWQG VTPAIYRHVV YSGGRMVTYE HLREVVFGKS EDEHYPLWKS VIGGMMAGVI GQFLANPTDL VKVQMQMEGK RKLEGKPLRF RGVHHAFAKI LAEGGIRGLW AGWVPNIQRA ALVNMGDLTT YDTVKHYLVL NTPLEDNIMT HGLSSDLVGS HKAIQ
Target Information
UCP4 (Uncoupling Protein 4) is a 323 amino acid mitochondrial carrier protein belonging to the large mitochondrial substrate carrier family with three Solcar repeats. It facilitates anion transfer across the mitochondrial membrane and proton re-entry, reducing mitochondrial membrane potential and contributing to thermoregulatory heat production. UCP4 uncouples oxidative phosphorylation from ATP synthesis, dissipating energy as heat. It is primarily expressed in adult and fetal brain, with lower levels in spinal cord, corpus callosum, and substantia nigra.
⚠ WARNING:
This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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