Thermo Fisher Scientific GluD1 Polyclonal Antibody
Thermo Fisher Scientific GluD1 Polyclonal Antibody는 인간 및 설치류 반응성을 가진 토끼 유래 IgG 항체입니다. Western blot, IHC, SPR 등 다양한 분석에 사용 가능합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 0.5 mg/mL 농도입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1.0 µg/mL | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Surface Plasmon Resonance (SPR) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human Glutamate Dehydrogenase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688379 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%
Target Information
Glutamate dehydrogenase (GluD1) is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. It plays an important role in regulating amino acid-induced insulin secretion. The enzyme is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are associated with congenital hyperinsulinism.
Alternative splicing results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of the enzyme. Related pseudogenes have been identified on chromosomes 10, 18, and X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 정보: PA5-69381_GluD1_P00367-1_Rabbit.svg, PA5-69381_GluD1_P00367-1_Rabbit_PDP.jpeg)
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