Thermo Fisher Scientific SUV39H2 Polyclonal Antibody
SUV39H2 단백질을 표적으로 하는 Thermo Fisher의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC(P)에서 1:20~1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 안정적. 연구용 전용 제품.
- 카탈로그번호
- PA563450
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SUV39H2 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SUV39H2. Recombinant protein control fragment (Product #RP-103302). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648099 |
Product Specific Information
Immunogen sequence:
NTVDLEGPPS DFYYINEYKP APGISLVNEA TFGCSCTDCF FQKCCPAEAG VLLAYNKNQQ IKIPPGTPI
Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 87%
Target Information
The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-63450_SUV39H2_Q9H5I1-1_Rabbit.svg)
(이미지: PA5-63450_SUV39H2_Q9H5I1-1_Rabbit_PDP.jpeg)
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