Thermo Fisher Scientific RRAD Polyclonal Antibody
RRAD 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 반응성. IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human RRAD, amino acids 211–308 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Ras-encoded family of proteins bind GDP and GTP with high affinity and possess low intrinsic GTPase activity, which increases over 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC21, RASL11B, and Rad (Ras associated with diabetes) GTPase.
Rad GTPase is a GTP-binding protein similar to Ras but with unique features. Unlike other small GTPases, Rad GTPase lacks typical prenylation motifs at its C terminus. It binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity, and cannot be stimulated by known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle, and lung tissues, and is overexpressed in skeletal muscle tissue of individuals with type II diabetes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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