Thermo Fisher Scientific PEG3 Polyclonal Antibody
Thermo Fisher Scientific의 PEG3 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. KLH 접합 합성 펩타이드 면역원으로 제작된 Rabbit IgG 형태의 액상 항체로, 고순도 Protein A 정제 및 안정적 저장이 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PEG3, amino acids 1501–1588 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In humans, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5′ exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5′ exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3.
In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons.
Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and involvement in tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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