
Thermo Fisher Scientific RLA-DQ Monoclonal Antibody (2C4)
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Applications
Tested Dilution
Publications
Flow Cytometry (Flow)
Assay-Dependent
Product Specifications
Species Reactivity
Rabbit
Host/Isotype
Mouse / IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2C4
Immunogen
Rabbit spleen cells
Conjugate
Unconjugated Unconjugated Unconjugated
View additional formats
Form
Liquid
Concentration
0.5 mg/mL
Purification
purified
Storage buffer
BBS, pH 8.2, with proprietary stabilizer
Contains
no preservative
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745706
Target Information
The monoclonal antibody 2C4 reacts with RLA-DQ-transfected cells, but not with RLA-DR-transfected cells. In normal adult rabbits, the antibody reacts with 30-60% of peripheral blood leukocytes. It has also been reported that the antibody stains lymphocytes and macrophages in the spleen, lymphocytes in the thymic medulla and some cells in the cortex, Kupffer cells in the liver, and synovial lining cells (e.g., infiltrating macrophages) in inflamed synovium. DQ alpha transcripts have been detected in bone marrow and spleen and to a lesser extent in appendix, lymph nodes, and other organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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