Thermo Fisher Scientific CLASP2 Monoclonal Antibody (KT68)
CLASP2 단백질을 인식하는 Rat 모노클론 항체로 Western blot 및 Immunoprecipitation에 적합. Human 및 Mouse 시료 반응성. Protein G로 정제된 1 mg/mL 액상 제품. 세포 이동과 미세소관 안정화 연구용.
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Thermo Fisher Scientific CLASP2 Monoclonal Antibody (KT68)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KT68 |
| Immunogen | Recombinant Mouse Clasp2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093300 |
Product Specific Information
This product was used in an Indirect ELISA.
Target Information
CLASP2 is a microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. It is required for the polarization of cytoplasmic microtubule arrays in migrating cells toward the leading edge. CLASP2 may act at the cell cortex to enhance the rescue frequency of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated by phosphatidylinositol 3-kinase signaling. CLASP2 also performs a similar stabilizing function at the kinetochore, essential for bipolar chromosome alignment on the mitotic spindle.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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