Thermo Fisher Scientific ELAC2 Polyclonal Antibody
ELAC2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, Human, Mouse, Rat에 반응. KLH 결합 합성 펩타이드(aa 88-190) 면역원 사용, 고순도 Protein A 정제 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ELAC2, amino acids 88–190 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ELAC2 encodes a protein with a C-terminal domain exhibiting tRNA 3′ processing endoribonuclease activity, catalyzing the removal of the 3′ trailer from precursor tRNAs. The protein interacts with activated Smad2 and its nuclear partner forkhead box H1 (FAST-1). Reduced expression can suppress TGF-β induced growth arrest. Mutations in ELAC2 are associated with increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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