Thermo Fisher Scientific C9orf114 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 163-340 of human C9orf114 (NP_0574742) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C9orf114,uniProtId:Q5T280-1,ncbiNodeId:9606,antigenRange:163-340,antigenLength:376,antigenImageFileName:PA5-116840_C9orf114_Q5T280-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116840_C9orf114_Q5T280-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901471

Product Specific Information

Positive Samples: U-87MG, K-562

Immunogen sequence: HQDLQFAGLL NPLDSPHHMR QDEESEFREG IVVDRPTRPG HGSFVNCGMK KEVKIDKNLE PGLRVTVRLN QQQHPDCKTY HGKVVSSQDP RTKAGLYWGY TVRLASCLSA VFAEAPFQDG YDLTIGTSER GSDVASAQLP NFRHALVVFG GLQGLEAGAD ADPNLEVAEP SVLFDLYV

Target Information

C9orf114 is a protein coding gene. Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.