Thermo Fisher Scientific C9orf114 Polyclonal Antibody
C9orf114 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ELISA에 사용 가능. 인간 및 랫트 반응성. 친화 크로마토그래피로 정제되었으며, PBS/glycerol 용액 형태로 제공. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 163–340 of human C9orf114 (NP_0574742) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.37 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901471 |
Product Specific Information
- Positive Samples: U-87MG, K-562
- Immunogen sequence:
HQDLQFAGLL NPLDSPHHMR QDEESEFREG IVVDRPTRPG HGSFVNCGMK KEVKIDKNLE PGLRVTVRLN QQQHPDCKTY HGKVVSSQDP RTKAGLYWGY TVRLASCLSA VFAEAPFQDG YDLTIGTSER GSDVASAQLP NFRHALVVFG GLQGLEAGAD ADPNLEVAEP SVLFDLYV
Target Information
C9orf114 is a protein coding gene required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. It is also involved in chromosome alignment and may promote centrosome maturation by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. C9orf114 binds specifically to miRNA MIR145 hairpin and regulates MIR145 expression at a posttranscriptional level.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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