Thermo Fisher Scientific RAB23 Polyclonal Antibody
RAB23 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 액상 형태입니다. 세포 내 단백질 수송 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human RAB23 (amino acids 11–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Ras-related superfamily of guanine nucleotide-binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins play key roles in endocytosis and biosynthetic protein transport, mediating the movement of carrier vesicles between the endoplasmic reticulum, Golgi complex, and secretory vesicles.
Rab23 (also known as HSPC137) is a 237-amino-acid member of the Rab family localized to the cytoplasmic side of the cell membrane. It is involved in intracellular protein transport and small GTPase-mediated signal transduction.
Mutations in the Rab23 gene are associated with Carpenter syndrome (ACPS2), a condition characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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