Thermo Fisher Scientific POLR1C Polyclonal Antibody
POLR1C 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 단백질에 반응하며, 합성 펩타이드를 면역원으로 사용했습니다. 액상 형태로 0.5 mg/mL 농도이며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human POLR1C (aa 21–70) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610381 |
Product Specific Information
Peptide sequence:
VRNVHTTDFP GNYSGYDDAW DQDRFEKNFR VDVVHMDENS LEFDMVGIDA
Sequence homology:
Cow: 100%
Dog: 100%
Goat: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 86%
Rabbit: 100%
Rat: 100%
Zebrafish: 82%
Target Information
RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis.
RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, suggesting multiple signaling pathways are involved in Pol I transcription.
RPA16, RPA40, and RPA135 are subunits of Pol I that associate early during RNA Pol I assembly.
RPA40 is essential for the function and integrity of the complex and is also a crucial subunit of RNA polymerase III (Pol III).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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