Thermo Fisher Scientific Thrombopoietin Recombinant Rabbit Monoclonal Antibody (2)
인간 Thrombopoietin(THPO)에 특이적인 재조합 토끼 단클론 항체. ELISA에 적합하며 높은 특이성과 일관된 로트 간 품질 제공. 보존제 무첨가로 필요 시 sodium azide 추가 권장. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilution
- Application: ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2 |
| Immunogen | Recombinant Human THPO protein (Ser22–Gly353) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786876 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal-origin-free formulation
- Broader immunoreactivity due to large rabbit immune repertoire
This antibody has specificity for Human THPO.
Target Information
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) regulates platelet production by acting on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor MPL (CD110) activates signaling pathways including JAK/STAT, MAPK, and PI3K/AKT, leading to megakaryocyte proliferation and differentiation, and ultimately platelet formation (thrombopoiesis).
Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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