Thermo Fisher Scientific MYH7 Polyclonal Antibody
MYH7 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, IP에 적합. 인간 시료에서 반응하며, 항원 친화 정제 방식으로 고순도 확보. 심근 및 골격근 관련 연구용으로 사용 가능. 연구용 한정 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 5–10 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human MYH7 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866993 |
Target Information
Muscle myosin is a hexameric protein composed of two heavy chain subunits, two alkali light chain subunits, and two regulatory light chain subunits.
This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin, expressed predominantly in normal human ventricle and in skeletal muscle tissues rich in slow-twitch type I fibers.
Alterations in MYH7 expression are associated with changes in cardiac contractile velocity and are influenced by thyroid hormone levels and hemodynamic stress.
Mutations in MYH7 are linked to familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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