Thermo Fisher Scientific Vimentin Recombinant Rabbit Monoclonal Antibody (BLR100G)
Thermo Fisher Scientific의 Vimentin Recombinant Rabbit Monoclonal Antibody (BLR100G)는 인간 및 생쥐 시료에 반응하는 고순도 재조합 항체입니다. Western blot, IHC, ICC/IF에 적합하며, HEK293 발현 시스템에서 생산되었습니다. 연구용으로 세포 골격 및 단백질 수송 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- 1:100 - 1:500
Immunocytochemistry (ICC/IF)
- 1:100 - 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR100G |
| Immunogen | Peptide representing a region between residue 325 and 375 of human Vimentin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 7.8–8.6, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular protein transport between the nucleus and plasma membrane. Vimentin, along with desmin, is expressed in early cellular development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by serving as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin by protein kinase leads to filament breakdown and cytoskeletal changes that facilitate cholesterol transport to mitochondria, enhancing steroid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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